Thursday, January 2, 2020

All About Dactinomycin

Dactinomycin is a chemotherapy agent belongs to the category of “antitumor antibiotic” Dactinomycin is available as 0.5mg Injection. dactinomycin 0.5 mg is recommended for the treatment of several types of cancer as per following details:
  • Gestational trophoblastic neoplasia
  • Wilms' tumor
  • Testicular cancer
  • Childhood Rhabdomyosarcoma
  • Ovarian (germ cell) cancer
  • Gestational trophoblastic neoplasm
  • Ewing's sarcoma
  • Metastatic testicular tumors (non seminomatous)
  • Gestational trophoblastic neoplasm
  • Locally recurrent or loco regional solid tumors (sarcomas, carcinomas and adenocarcinomas)
  • Soft tissue sarcoma
  • Osteosarcoma

The innovator brand of Dactinomycin is Cosmegen. Cosmegen was approved by FDA USA in 1982. Dactinomycin is available as .5 mg / vial

There are many generic brands of Dactinomycin available in India as per follows:

  1.  Dacilon 0.5mg Injection, Celon Labs
  2.  Actinocin 0.5mg Injection, Neon Laboratories Ltd
  3.  Tinowel 0.5mg Injection, Getwell Oncology Pvt Ltd
  4. Dacmozen 0.5mg Injection, VHB Life Sciences Inc
  5. Daltepin – Intas
  6.  Dactino - Chandra Bhagat Pharma

Dactinomycin0.5mg Injection works by interfering with the growth of cancer cells, which are eventually destroyed. Dactinomycin is given under the supervision of a healthcare professional and should not be self-administered. Dactinomycin might be given as a single therapy or in combination with some other medication.

There are many countries where Dactinomycin is not available or approved. Patients from those countries can import medicine on named patient bases. They have to take import permission from their Government before importing the product. They have to provide their prescription and id proof before importing the product. It is always better to check the credential of the exporter before importing the product.


There is another way for the patient to get access to generic medicines from India. Patients can travel to India for consultation with a qualified Doctor and based on the prescription, they can buy 3-6 months of therapy. Patients need to know the legal requirement of their domicile countries before taking medicine along with them. It is advisable not to buy medicine which contains narcotic substance.

A generic medicine is a broad term. The patient/buyer should check the Credibility of the manufacturer before buying the product.

What is Dactinomycin? 
Dactinomycin or actinomycin D, is a chemo drug used to treat certain cancers including Wilms tumor, Ewing's sarcoma, trophoblastic neoplasm, rhabdomyosarcoma, testicular cancer, and certain types of ovarian cancer.

What class of drug is Dactinomycin?
Dactinomycin falls under the cytotoxic antibiotic family of medications.

How should Dactinomycin be administered? 
Dactinomycin or Actinomycin D injection should be administered by injection into a vein.

Where can I Buy Generic Dactinomycin .5 mg in India?
Patients from all over the world can buy generic Dactinomycin from Pharmacy shops in India. Patients need to consult Hematologist / Oncologists / Physician before starting treatment.     

Can we buy Dactinomycin online?
Dactinomycin is a prescription medicine. The patent should start treatment with Dactinomycin after consultation with treating Physician

What are the commonly reported side effects due to Dactinomycin? 
The most commonly reported side effects include bone marrow suppression, vomiting, muscle pains, mouth ulcers, hair loss, liver problems, and infections. 

What are the long term side effects of Actinomycin D? 
Certain actinomycin D long term side effects may include:
  • bone marrow injury
  • delayed healing
  • congestive heart failure exacerbation
  • toxic liver injury
  • unexplained or lingering fatigue
  • susceptibility to infection
  • high risk of new cancer tumors (including leukemia)
  • limb constriction
  • renal failure 
  • skin deformity/scarring
  • increased risk of infertility

What if Dactinomycin is used in pregnancy? 
Use of Dactinomycin in pregnancy may harm the baby.

What is the price of Actinomycin D injection? 
The actinomycin D injection price for patients usually varies depending on several different factors, such as geographic location, severity of disease, and the appropriate dactinomycin dosage.


NOTE: The information provided in this article named All About Dactinomycin, is only for informational purposes and is not served as a substitute for the medical treatment, consultation, diagnosis, of a qualified doctor. 



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