Trodelvy (sacituzumab govitecan-hziy) is a therapeutic medicine used for the treatment of patients with HE+Ve/HER2-Ve metastatic breast cancer, metastatic triple-negative breast cancer (mTNBC), and locally advanced or metastatic urothelial cancer (mUC). Trodelvy is commercially available in 180 mg and 200 mg dosage strengths. While this medicine can be a promising therapy, it's necessary to know potential warnings and precautions related to its use:
Neutropenia: Trodelvy 180 mg/200 mg vials may be responsible for causing a reduction in WBC counts, specifically neutrophils, which can enhance the risk of infections. Regular blood tests are necessary to monitor these levels.
Diarrhea: Critical diarrhea can occur with the use of Trodelvy therapy. Individuals need to take anti-diarrheal medicines and follow their doctor's instructions to effectively manage diarrhea.
Interactions: Let your clinician know about all medicines, supplements, and herbal products you are using, as Trodelvy treatment may interact with other medicines.
Pregnancy and Nursing: Trodelvy injection can be responsible for harm to an unborn baby, so it's important to avoid pregnancy during therapy and use promising birth control. It's also advisable to avoid breastfeeding.
Infusion Reactions: Infusion-related reactions may occur during treatment. Doctors are prepared to manage infusion reactions in a medical setting.
Liver Function: Trodelvy 200 mg/180 mg vials can be responsible for affecting liver function, so regular liver function tests are crucial throughout treatment.
Hematologic Toxicity: This medicine may cause thrombocytopenia and anemia, which require precise monitoring as well as management.
Interstitial Lung Disease (ILD): ILD is a rare but critical lung complication that has been reported with Trodelvy treatment. Report promptly in case of any new or worsening respiratory signs and symptoms.
Hypersensitivity Reactions: Seek prompt medical attention in case of signs of hypersensitivity, such as chills, fever, or difficulty breathing.
Note: Always follow your doctor's recommendations and report any unusual signs and symptoms or adverse reactions immediately when using Trodelvy injection. This information is for general purpose; consult your doctor and medicine label for comprehensive information and personalized guidance.
Reference:
https://www.trodelvy.com/
