Tuesday, November 19, 2019

Best Treatment for wilson's disease in india

Trientine HCl (Brand name: Syprine) - Manufactured by Merck Sharp & Dohme Research

FDA-approved Treatment of patients with Wilson's disease who are intolerant, or inadequately responsive to penicillamine.

(Wilson disease is a rare genetic disorder that is characterized by the accumulation of copper in the body Because high level of copper are toxic to tissues and organs, this build-up can lead to damage of the liver, brain and eyes. Signs and symptoms of Wilson disease include chronic liver disease, central nervous system abnormalities, and psychiatric (mental health-related) disturbances. It is caused by a mutation of the ATP7B gene and is inherited in an autosomal recessive manner.)


How much does Trientine cost?

Innovator brand Syprine cost will goes approx. 3500 USD/Pack and Trientine Hydrochloride generic version will cost approx. 300 to 500 USD/Pack (100 Capsules) for 250 mg and 300 mg dosage.

Has a generic version of Syprine been approved?
Yes. The following products are equivalent to Syprine:
Manufacturer: AMNEAL PHARMS LLC (dosage available- 250 mg). Approval date: February 8, 2019
Manufacturer: DR REDDYS LABS LTD (dosage available- 250 mg). Approval date: July 3, 2019
Manufacturer: KADMON PHARMS LLC (dosage available- 250 mg). Approval date: September 16, 2019
Manufacturer: MSN LABS PVT LTD (dosage available- 250 mg). Approval date: May 22, 2019
Manufacturer: NAVINTA LLC (dosage available- 250 mg). Approval date: January 16, 2019
Manufacturer: PAR PHARM INC (dosage available- 250 mg). Approval date: September 25, 2019
Manufacturer: WATSON LABS TEVA (dosage available- 250 mg). Approval date: February 7, 2018
Manufacturer: ZYDUS PHARMS (dosage available- 250 mg). Approval date: April 26, 2019
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