Monday, February 3, 2020

Procarbazine and Hodgkin's Lymphoma

Procarbazine (P Carzine) falls under the group of drugs known as alkylating agents, which interfere with the growth of certain types of cells in the body.

It is prescribed as one of the chemo drugs in the treatment of certain types of cancers. 
In adult patients, procarbazine hydrochloride capsules are used on its own or together with other drugs for the treatment of Hodgkin’s disease (a cancer of the lymph glands).
In children (aged 2 to 18 years), it is prescribed together with other drugs in order to treat Hodgkin’s disease.

What are the procarbazine side effects?

The common side effects are as:
  • Low blood counts
  • Nausea
  • Vomiting
  • Headaches
  • Dizziness
  • Hallucinations
  • Sleep disturbances
  • Diarrhoea
  • Apart from that, the occasional procarbazine side effects are as follows:
  • Mouth sores
  • Skin rash
  • Emotional changes
How to Take Procarbazine Dose?

Always take this medicine exactly as your healthcare provider has told you. Check with your healthcare team in case you are unsure.

The procarbazine capsule is usually given together with the other medications and it is crucial that you (or your child) take each drug at the right time. Sometimes procarbazine treatment starts with a tiny dose (1 capsule per day) and is increased each day up to a maximum of 6 capsules per day.

Pregnancy: This drug should not be consumed during the first trimester of the pregnancy. Its use is also not recommended throughout the remainder of the period of pregnancy. 

Breast-feeding: Do not take P carzine 50mg in case you are breast-feeding.

Fertility: This medicine may be responsible for causing infertility which might mean that you are not able to have children. Ask your healthcare practitioner for instructions prior to taking any drug.

Driving and using machines: The medication procarbazine 50mg may be responsible for causing drowsiness. In case affected you need not drive or use machinery. 

Storage: Procarbazine 50mg Capsules should not be removed from their blister packaging until you are ready to use them. Avoid mixing loose capsules with other loose capsules or tablets. Should be stored in the original container to protect from the moisture. Avoid storing above 25°C.


Where can I buy P-carzine (generic procarbazine hydrochloride) in India?

The procarbazine 50mg price in india is absolutely reasonable, and can be bought from any WHO-GDP as well as ISO certified pharmaceutical company. Prices may vary from non-branded to branded drugs.
The procarbazine cost (P carzine 50 mg) for a strip of 10 capsules is around 337 INR. 

NOTE: The piece of information provided about Procarbazine and Hodgkin's Lymphoma in this article is just for informational purposes and is not served as a substitute for the medical treatment, consultation, diagnosis of an experienced or qualified healthcare practitioner. And in order to know more about this medicinal product, click on the procarbazine 50mg.



FDA Approved medicines in order to treat Hodgkin`s Lymphoma:
  • Ambochlorine (Chlorambucil)
  • Adcetris (Brentuximab Vedotin)
  • ABVD (drug combination including Adriamycin, Bleomycin, Vincristine Sulfate, and Dacarbazine)
  • ABVE (drug combination including Adriamycin, Bleomycin, Vincristine Sulfate, and Etoposide)
  • ABVE-PC (drug combination including Adriamycin, Bleomycin, Vincristine Sulfate, Etoposide, Prednisone, and Cyclophosphamide)
  • BEACOPP (drug combination including Bleomycin, Etoposide, Adriamycin, Cyclophosphamide, Oncovin, Procarbazine and  Prednisolone)
  • Becenum (Carmustine)
  • BiCNU (Carmustine)
  • Blenoxane (Bleomycin)
  • Bleomycin injection
  • Leukeran (Chlorambucil)
  • Brentuximab Vedotin
  • Carmubris (Carmustine)
  • Carmustine
  • DTIC-Dome (Decarbazine)
  • Dacarbazine
  • Cytoxan (Cyclophosphamide)
  • Cyclophosphamide
  • Claflen (Cyclophosphamide)
  • Chlorambucil
  • Doxorubicin Hydrochloride
  • ICE (drug combination including Ifosfamide, Carboplatin, and Etoposide)
  • OEPA (drug combination including Oncovin, Etoposide, Prednisone, and Adriamycin)
  • OPPA (drug combination including Oncovin, Procarbazine Hydrochloride, Prednisone, and Adriamycin)
  • Prednisone
  • Procarbazine Hydrochloride
  • STANFORD V (drug combination including Cyclophosphamide, Mechlorethamine or Ifosfamide in addition to Doxorubicin, Vinblastine, Vincristine, Bleomycin, Etoposide, and Prednisone)
  • VAMP (drug combination including Vincristine Sulfate, Adriamycin, Methotrexate, and Prednisone)
  • Velban (Vinblastine Sulfate)
  • Velsar (Vinblastine Sulfate)
  • Vinblastine Sulfate
  • Vincasar PFS (Vincristine Sulfate)
  • Vincristine Sulfate
Affecting Terms:
In this segment, there are few terms are given that might be the probable factor that could increase Hodgkin`s Lymphoma. Which are as follows:

  • Age: Hodgkin`s Lymphoma may affect all the age group people but mostly between 20-35 as well as those who persons are above 55 years old.
  • Genetics: If someone having any Family Background then there are many chances of this disease.
  • Being male: Hodgkin`s Lymphoma most commonly hit to males in comparison to the females.
FAQ's

What were your first symptoms of Hodgkin's lymphoma?

The most common symptom is enlargement or swelling of one or more lymph nodes, causing a lump under the skin, usually doesn't hurt. It's most often on the side of the neck, in the groin or armpit. 

Is Hodgkin's lymphoma a death sentence?

The existing treatments are quite effective for certain types of lymphoma, specifically HL (Hodgkin's lymphoma), in case detected early on. In fact, the medical advances over the last some years have made HL one of the most curable forms of cancer.

What are hodgkin's lymphoma stages? 

As with most other cancers, there are basically 4 different stages of lymphoma: I, II, III, & IV.

How long is it possible to live after Hodgkin's lymphoma treatment?

The 5-year SR refers to the% of patients, on behalf of the stage of their cancer at diagnosis, who live at least 5-years following the hodgkin lymphoma treatment. Numerous of these patients generally live longer than the 5-years.

Is Hodgkin lymphoma curable?

Treatment for the HL (Hodgkin lymphoma) is highly effective and most patients with the disease are eventually cured.

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