In 1961,vincristine was isolated for the first time. It is specifically a vinca alkaloid, found from the Madagascar periwinkle Catharanthus roseus.
Vincristine also can be addressed as leurocristine. It comes in the market under the brand name Oncovin, and falls under the chemotherapy medication.
The vincristine injection is an important chemotherapeutic agent properly administered intravenously in the treatment of many patients with leukemia or lymphoma. However, improper administration of vincristine dose is fatal.
Vincristine is always administered intravenously. When it reaches to the blood, it is effective in order to block the growth of cancer by preventing cells from dividing. However, vincristine fda approved drug is a neurotoxin that may be responsible for causing peripheral neuropathy when administered intravenously and profound neurotoxicity if administered into the spinal fluid, which flows around the spinal cord and brain.
Many patients who receive vincristine 1 mg have a treatment regimen that includes other chemotherapy drugs that are administered intrathecally, or injected into the spinal fluid with a syringe. If this medication is by fault given into the spinal fluid, it is uniformly fatal, and may cause neurological defects, ascending paralysis, and death, usually within a week.
If you are pregnant or become pregnant during vincristine uses, you should notify your doctor immediately.
This product should be refrigerated between 2°–8°C (36°–46°F). Discard unused solution. Protect from light. Store Upright.
The vincristine injection price may vary from branded to non-branded drugs. A WHO-GDP & ISO certified pharmaceutical wholesaler can provide you the best vincristine price around 50 INR to 250 INR.
Note: Before starting treatment with vincristine, consult a physician. To know more about this product, please read full prescribing information.
FAQ's
What is vincristine used for?
This chemotherapy drug is recommended to be used for the treatment of a number of types of cancer, includes:
- Acute lymphocytic leukemia
- Acute myeloid leukemia
- Hodgkin's disease
- Neuroblastoma
- Small cell lung cancer
What are the side effects of vincristine?
In patients with this medication some common side effects may occur, which may include change in sensation, constipation, hair loss, difficulty walking, and headaches. Although, some serious vincristine side effects may include lung damage and neuropathic pain.
How long do side effects of vincristine last?
In case single, vincristine doses are given on the weekly basis, the side effects of leukopenia, constipation and neuritic pain may appear but are usually for short term (less than 1 week). In case of reduction in dosage, these side effects may be lessened or disappeared.
How do you inject vincristine?
Vincristine is given intravenously. Patients have this treatment with the help of a drip into their arm or hand. Doctor puts a small tube (a cannula) into veins and connects the drip to it.
Patients might require a central line. This is a kind of long plastic tube that provides the medications into a large vein, either in the chest or through a vein in an arm. It stays in while patients are taking treatment, perhaps for some months.
How often is vincristine given?
Vincristine injection is given by several dosing schedules from weekly to bi-weekly to monthly. The most appropriate schedule and the total number of treatment cycles may vary and depend on patients clinical circumstances.
How does vincristine work in the body?
Vincristine is a chemotherapy drug, falls under the group of medicines named vinca alkaloids. It specifically acts by stopping the cancerous cells from integrating into new cells. So, it helps in stopping the growth of cancer.
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