Bendamustine (Treanda), falls under an alkylating agent, which is specifically a chemotherapy drug recommended in order to treat chronic lymphocytic leukemia (CLL), multiple myeloma, and non-Hodgkin’s lymphoma. This drug comes in order to be given by injection into a vein.
In patients with bendamustine injection, some commonly reported adverse reactions include fever, low blood cell counts, nausea, loss of appetite, diarrhea, cough, and rash. Other severe adverse reactions due to this injection may include increased risk of infection, and allergic reactions. Administration during pregnancy may leave harmful effects on an unborn baby.
How Bendamustine Is Given: As an injection it should be given into the vein (intravenous, IV). Bendamustine does not come in the form of pills. The amount of drug that you will be given depends on several factors, including height as well as weight, general health or other health related complications, and cancer type or condition being treated. Your healthcare provider will determine the appropriate dose and also schedule.
What are some precautions should I follow?
Prior to start taking bendamustine injection,
- inform your healthcare practitioner in case you are allergic to bendamustine 100 mg, any other drugs, or any of its ingredients. Ask your healthcare practitioner for a list of the existing ingredients.
- inform your healthcare practitioner what prescription as well as nonprescription drugs, vitamins, nutritional supplements, and herbal products you are taking or want to take. Be sure to mention any of the following: ciprofloxacin, fluvoxamine, and omeprazole. Your healthcare team may need to change the doses of your drugs or monitor you carefully for adverse reactions. There are several drugs that may interact with this injection, so be sure in order to tell your healthcare provider about all the medicines you are consuming, even all those that are not appearing on this list.
- inform your healthcare practitioner in case you have or have ever had CMV, Hepatitis B virus infection, TB, herpes zoster, or kidney or liver disease.
- inform your healthcare practitioner in case you are pregnant or want to conceive a child, or if you want to father a child. You must use birth control in order to prevent pregnancy in yourself or your partner while on your treatment with bendamustine injection and for 90 days afterwards. Discuss with your healthcare team about birth control methods that will be suitable for you. In case you become pregnant while on bendamustine injection, contact your healthcare practitioner. Bendamustine injection may be responsible for causing harm to the fetus.
- Inform your healthcare professional in case you are breast-feeding. You should avoid breastfeeding while on your treatment with bendamustine injection.
- you must be aware that this injection may be responsible for making you tired. Avoid driving a car or operating machinery until you know how this drug affects you.
- inform your healthcare provider in case you use tobacco containing products. Smoking may reduce the effect of this medicine.
What do I need to do if I forget a dose?
Contact your healthcare practitioner immediately in case you are unable to keep an appointment in order to receive a dose of bendamustine injection.
NOTE: The information provided in this article is only for informational purposes and is not served as a substitute for the medical treatment, consultation, diagnosis, of a qualified healthcare practitioner.
FAQ’s
- What is General Information about Chronic Lymphocytic Leukemia?
- CLL is a type of cancer in which our bone marrow produces unwanted lymphocytes (a type of white blood cell).
- Leukemia may be responsible for affecting the red blood cells, white blood cells, as well as platelets.
- Signs as well as symptoms of cll leukemia include swollen lymph nodes and feeling tired.
- Tests that examine the blood are used for Chronic lymphocytic leukemia diagnosis.
How does chronic lymphocytic leukemia affect the body?
Chronic Lymphocytic Lymphoma is responsible for causing a slow increase in a certain sort of WBC named B lymphocytes, or B cells. Cancerous cells basically spread through the blood as well as bone marrow. It can also be responsible for affecting the lymph nodes or other organs such as the spleen and liver. Chronic lymphocytic lymphoma eventually may affect the functioning of bone marrow.
How common is chronic lymphocytic leukemia?
Chronic Lymphocytic Lymphoma is one of the most common types of leukemia in adults. It often occurs while or following middle age; it rarely develops in children.
What are the stages of CLL?
After the diagnosis of chronic lymphocytic leukemia, tests are done in order to find out whether the cancer has spread or not.
The following CLL stages are as:
- Stage 0
- Stage I
- Stage II
- Stage III
- Stage IV
This disease (CLL) is basically described as asymptomatic, symptomatic or progressive, refractory, or recurrent.
Can I return to work or my normal activities?
Returning to work or normal activities will depend on how you respond to the treatment. Every individual responds in a different way. Ask your healthcare team what is appropriate for you.
As you return to your work/daily activities, let your friends and caregiver assist you. Allowing friends and family to give moral and emotional support is quite helpful during your treatment.
What should I do if I am having adverse reactions from Bendamustine treatment?
Get in touch with your healthcare professional right away in case you have any adverse reactions. Don’t wait to circulate this information at your next office visit.
Will I lose my hair?
In a safety evaluation from a clinical study for chronic lymphocytic leukemia, hair loss occurred in 1 of the 153 patients treated with the bendamustine in comparison to 0 of the 143 patients treated with the chlorambucil. On behalf of an NHL study, hair loss occurred in 3 of the 100 patients treated with bendamustine HCL.
How much does bendamustine cost?
The average wholesale price (AWP) of bendamustine HCL (Bendit) is 3,643 INR for a supply of vial of 1 injection.
NOTE: The piece of information provided in this article about "Bendamustine: Frequently Asked Questions (FAQs)" is just for informational purposes and is not served as a substitute for the medical treatment, consultation, diagnosis, of an experienced or qualified healthcare practitioner.
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