All You Need To Know About Brentuximab Vedotin

About Brentuximab Vedotin: Brentuximab Vedotin is used to treat patients with: 

Hodgkin lymphoma (HL) that has come back following a stem cell transplant or following two types of chemotherapy if you cannot receive a stem cell transplant. 

Systemic anaplastic large cell lymphoma (sALCL) that comes back following the treatment with chemotherapy. 

HL at increased risk of continuing or returning, as additional treatment following an autologous stem cell transplant (ASCT). 

Dosage Forms: Brentuximab comes under the brand name drug Adcetris. It is available in a single-use vial containing 50 mg of brentuximab vedotin for injection.

Administration: The recommended dosage of brentuximab vedotin is administered as an intravenous infusion over 30 minutes.

Usual dose: The dose is 1.8 mg/kg. If you have mild liver disease, the dose may be 1.2 mg/kg. If you have more serious liver or serious kidney disease, brentuximab use should be avoided. If you weigh more than 100 kg, your dose will be calculated as if your weight was 100 kg. You will receive brentuximab at three week intervals. Treatment with brentuximab will be stopped in case your disease gets worse or if you experience unacceptable side effects. 

If you are receiving brentuximab after an ASCT (autologous stem cell transplant), your therapy should begin within 4 to 6 weeks after ASCT or recovery from ASCT. Treatment with this drug will continue for up to 16 doses or until then your disease gets worse or if you experience unacceptable adverse events.

Possible Side Effects: These are not the entire possible side effects you may feel when taking brentuximab vedotin. In case you experience any side effects not mentioned here, contact your healthcare team promptly. Common side effects associated with the use of brentuximab include:

• Nausea
• Vomiting
• Fatigue
• Diarrhea
• Shortness of breath
• Low red blood cell counts
• Low white blood cell counts

Certain other side effects you may experience, which are fever, hair loss, muscle pain and itching. These side effects may develop during and following therapy with adcetris 50 mg injection.

Precautionary Measures:

• Do not use brentuximab if you have a known allergy to the medicinal or non-medicinal ingredients. 
• Use of brentuximab should be avoided if you are currently on another drug named bleomycin. Bleomycin must be stopped prior to starting brentuximab injection. 
• Avoid using Brentuximab in case you have or have had PML (Progressive Multifocal Leukoencephalopathy).
• Females who may become pregnant should use minimum two reliable methods of birth control while on and for 6 months following therapy with adcetris. Promptly report to your doctor if you become pregnant while on therapy. 
• Breastfeeding is restricted while you are receiving brentuximab. It is not known if the medication can get into breast milk, and therefore, into the baby. 
• Males should consider an appropriate method of barrier contraception while on and for 6 months after treatment with brentuximab vedotin 60 mg.
• Certain medications and foods (like grapefruit juice) may be responsible for changing the level of anti-mitotic in the body.

Overdose: It is unlikely that you will receive excess brentuximab as you will be closely monitored by healthcare professionals during your infusion. In case of overdose, contact a health care practitioner, hospital emergency department or regional Poison Control Center promptly, even if there are no symptoms.

Missed Dose: If you miss your appointment to receive brentuximab dose, you need to make every effort in order to receive the missed dose very quickly. Doses should not be given less than three weeks apart.

Storage: Store Brentuximab at 2°C to 8°C in the original carton. Protect it from light. Keep out of reach and sight of children.

Price: The brentuximab price in India can vary. In order to know the exact price as well as the procurement deets, kindly get in touch with us today at 9650877511

Note: The information provided in the article named "All You Need To Know About Brentuximab Vedotin", is just for informational purposes and it is not responsible for serving as a substitute for the medical treatment, consultation, or diagnosis, of an experienced healthcare professional.

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