Arcalyst (Rilonacept)

• Medicine Name- Arcalyst 
• API- Rilonacept
• Strength- For injection: 220 mg of lyophilized powder in a single-dose vial for reconstitution
• Manufactured by- Kiniksa

Medicinal Uses

The interleukin-1 blocker ARCALYST (rilonacept) is prescribed for the following conditions in adults and children 12 years of age and older: 

Treatment of Cryopyrin-Associated Periodic Syndromes (CAPS), including Familial Cold Auto-inflammatory Syndrome (FCAS) and Muckle-Wells Syndrome (MWS).

Sustaining the remission of DIRA (Deficiency of Interleukin-1 Receptor Antagonist) in patients aged 10 years or older and in adults.

Treating adults and children 12 years of age and older for recurrent pericarditis (RP) and lowering their chance of recurrence

Recommended Dosage

• Administration:
• Given as a subcutaneous injection.
• For Conditions like CAPS, FCAS, MWS, and RP:

Adults:

• Loading Dose: 320 mg, two injections of 160 mg each.
• Maintenance Dose: 160 mg once weekly.
• Pediatric Patients (12 to 17 years):
• Loading Dose: 4.4 mg/kg (up to 320 mg), one or two injections.
• Maintenance Dose: 2.2 mg/kg (up to 160 mg) once weekly.

For DIRA:

Adults and Pediatric Patients (10 kg or more):

Dose: 4.4 mg/kg (up to 320 mg), one or two injections once weekly.

Patients should receive these injections as directed by their healthcare provider based on their age and specific condition.

Warning and Precautions:

Severe Infections: Patients using ARCALYST have reportedly experienced serious, sometimes fatal infections. In patients with ongoing or persistent infections, do not start ARCALYST medication. In the event that a patient gets a serious infection, stop treatment. 

Hypersensitivity Reactions: Stop giving ARCALYST and start the proper treatment if a hypersensitivity reaction happens. 

Vaccinations: Steer clear of live shots. As per current guidelines, update recommended vaccines prior to starting therapy.

Documentation & Availability in India:

If you are considering the import of Arcalyst (Rilonacept) to India, please be aware that Arcalyst can be imported by patients or government hospitals solely in the name of the patients. The following documentation is essential for the successful import of this medication:

Required Documentation for Import:

• A valid prescription from a qualified medical practitioner.
• Diagnostic reports of the patient.
• Government-issued identification proof for the patient, as recognized by the Government of India.

Order Confirmation Process: 

The order for Arcalyst (Rilonacept) will be confirmed upon the receipt of the following documents:

• A valid prescription from a qualified doctor.
• An import permit, if applicable.

Availability of Arcalyst (Rilonacept)  in India: 

Arcalyst (Rilonacept) is classified as a prescription pharmaceutical drug. Consequently, it legally requires a medical prescription to be dispensed. Indian Pharma Network (IPN) specializes in facilitating the import of cancer medicines through named patient supply (NPS), ensuring transparency and authenticity by sourcing from reputable suppliers in the USA, Canada, Europe, and Australia.

Arcalyst (Rilonacept) can be made accessible to patients, doctors, and hospitals in various cities across India, including but not limited to Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Srinagar, Jammu, Jaipur, Chandigarh, Ludhiana, Noida, Gurgaon, Lucknow, and Pune. To confirm an order, a valid prescription from a doctor and an import permit will be required.

IPN (Indian Pharma Network) is dedicated to facilitating the supply of Arcalyst (prescription medicines) to locations both within India and worldwide, while adhering to relevant legal requirements.

Our commitment lies in assuring quality and timely delivery to meet the healthcare needs of patients and medical professionals across the globe.

Sourcing & Delivery: 

Indian Pharma Network is proficient in sourcing Arcalyst (Rilonacept) from around the world and ensuring efficient delivery to patients. We provide worldwide access to the best available treatments and expedite prescription dispensing and delivery, with all prescriptions being dispensed and scrutinized by registered pharmacists before dispatching them to the patient's address, exclusively from New Delhi, India.

FAQ's

What is the medicine ARCALYST used for?

ARCALYST (Rilonacept) is an interleukin-1 blocker prescribed for Cryopyrin-Associated Periodic Syndromes (CAPS), sustaining remission of Deficiency of Interleukin-1 Receptor Antagonist (DIRA), and treating recurrent pericarditis (RP) in adults and children 12 years and older.

What is the recommended dosage for ARCALYST?

The dosage varies for different conditions. For CAPS, FCAS, MWS, and RP, adults usually start with a loading dose of 320 mg, followed by a maintenance dose of 160 mg weekly. Pediatric patients follow weight-based dosing.

How is ARCALYST administered?

ARCALYST is administered as a subcutaneous injection.

Are there any warnings or precautions for ARCALYST use?

Yes, severe infections have been reported, and patients with ongoing infections should avoid starting ARCALYST. Hypersensitivity reactions may occur, and live vaccinations should be avoided during therapy.

What precautions are needed for the import of ARCALYST to India?

Import requires a valid prescription, diagnostic reports, and government-issued ID for the patient. An import permit, if applicable, is essential.

How can ARCALYST be ordered in India?

To order, a valid prescription and import permit are needed. The order will be confirmed upon receipt of these documents.

Is ARCALYST available in India?

Yes, ARCALYST is available in India through Indian Pharma Network (IPN), ensuring compliance with legal requirements and facilitating efficient delivery.