Breast Cancer - Stage 4 Breast Cancer Survival Rate

 What is Palbociclib

palbociclib 125 mg (trade name IBRANCE) is one of the leading medicine for the treatment of various Breast Cancer. It helps to get rid of against Hormone Receptor (HR-Positive and HER- Negative) Breast Cancer Treatment. Palbociclib works by resisting or reducing the growth of cancer cells. It is effective for Metastatic Breast Cancer Treatment. palbociclib 125 mg is a Chemotherapy drug that prevents developing cancer cells.


Palbace 125 mg Capsule Prescribed for

• Palbace 125 mg Capsules are basically used for Breast Cancer Treatment.
• It can be suitable for up to the age of 18 years.
• It helps against Hormone Receptor (HR-Positive and HER- Negative) Breast Cancer.

How to use Palbace 125 mg Capsule

• The general way of using this medication by mouth after having food as prescribed by your doctor.
• Strictly avoid grapefruit products.
• Gulped the whole Capsule, instead of chew.
• Neither Crush the Capsule nor open it.
• No need to consume damage or broken Capsules.
• Dosage would be based upon your medical circumstances.
• During swallow, if you puked, just skip the day. Do not take another tablet in order to fulfill the cycle. Just take it the next day.
• For better benefits take this medicine at the same time every day.

Palbace 125 mg price in India

Palbace125 mg capsules are an anti-cancer medicine used in the treatment of breast cancer. The cost of this medicine is INR 95,000 which is $1380 in Abroad.
Palbace is the Innovator medicine, and the manufacturer of this drug is Pfizer.

Dose Information:

Palbace (IBRANCE) is typically a program of 4 weeks. One has to take a single tablet consecutive for the 3 weeks (21 days) followed by 1 week off.
During consumption make sure you`re taking proper rest as well as proper sleep.
Ibrance is not for the people who are in their tender age, minimum criteria of consumption of this medicine are that the patient should be at least 18 years old.

What not to do during consumption:

If you`re diagnosed with this disease, there are numerous things need to avoid. Which is as follows:

• Avoid Breastfeeding: Breastfeeding can affect the infant, so avoid Breastfeeding during consumption days.
• Avoid Alcohol: Alcohol might be affected in a hazardous way. If you want to take Alcohol please consult your doctor prior to consumption.
• Do not consume it in Pregnancy: If someone conceiving a baby then do not use this medicine. It could be dangerous for an unborn baby. Please consult your doctor.
• Driving: Side effects of Palbace might affect one`s ability to drive. Although sometimes it may be caused by fatigue in a number of people.

Side Effect of Palbace: 

Due to the consumption of Palbace 75mg, 100mg & 125mg few of the side effects can happen, which are as follows:
• Fatigue
• Ulcer in mouth
• Puke
• Nausea
• Rashes
• Fever & Headache
• Anemia
• Lack of Strength
• Hair Loss
• Infections
• Loss in Appetite
• Unexpected Weight Loss
• Decrease of White Blood Cells
• Diarrhea

Because of the side effect, your treatment could get affected or it might be possible that your doctor suggests permanently discontinue your treatment.


Medicine for Breast Cancer Treatment

People who are diagnosed with breast cancer generally get various kind of treatment:
• Chemotherapy
• Surgery
• Hormonal Therapy
• Radiotherapy

Palbace is available in the three-dosage which are 75 mg, 100 mg & 125 mg.Also use  letrozole 2.5 mg Medicine for Breast Cancer Treatment.

With the regular use of Palbace the developing cancer cells stopped.
The Price of Palbace 75 mg in India INR 95,000. (INR 95,000 is the Price of the ibrance 125 mg in India).


If you`re looking forward to purchasing the Palbace 75mg, 100mg & 125 mg, just go towards the well known and fastest-growing pharmaceuticals company named Dotcom Pharma Private Limited which is a group company of IKRIS Pharma Network.  The URL of its official website is given as-  www.ikrispharmanetwork.com

Additional Information:

• Keep safe such kind of all the medicines.
• Placed it out of reach of the children.
• Never share your medicine with someone else.
• Always consult your doctor at a regular period of time for better health results.
• Do not consume this medicine in a larger quantity.
• Neither takes it in lesser quantity, just take it as your doctor has prescribed.
• Meet your doctor if you start feeling doubtful side effects.
• Do not stop using it without the suggestion of the your doctor.


READ:-  

Breast Cancer and Their Treatments 

Medicine for Breast Cancer Treatment

All about breast cancer

Procarbazine and Hodgkin's Lymphoma

Procarbazine (P Carzine) falls under the group of drugs known as alkylating agents, which interfere with the growth of certain types of cells in the body.

It is prescribed as one of the chemo drugs in the treatment of certain types of cancers. 

In adult patients, procarbazine hydrochloride capsules are used on its own or together with other drugs for the treatment of Hodgkin’s disease (a cancer of the lymph glands).

In children (aged 2 to 18 years), it is prescribed together with other drugs in order to treat Hodgkin’s disease.

What are the procarbazine side effects?

The common side effects are as:

• Low blood counts
• Nausea
• Vomiting
• Headaches
• Dizziness
• Hallucinations
• Sleep disturbances
• Diarrhoea
• Apart from that, the occasional procarbazine side effects are as follows:
• Mouth sores
• Skin rash
• Emotional changes

How to Take Procarbazine Dose?

Always take this medicine exactly as your healthcare provider has told you. Check with your healthcare team in case you are unsure.

The procarbazine capsule is usually given together with the other medications and it is crucial that you (or your child) take each drug at the right time. Sometimes procarbazine treatment starts with a tiny dose (1 capsule per day) and is increased each day up to a maximum of 6 capsules per day.

Pregnancy: This drug should not be consumed during the first trimester of the pregnancy. Its use is also not recommended throughout the remainder of the period of pregnancy. 

Breast-feeding: Do not take P carzine 50mg in case you are breast-feeding.

Fertility: This medicine may be responsible for causing infertility which might mean that you are not able to have children. Ask your healthcare practitioner for instructions prior to taking any drug.

Driving and using machines: The medication procarbazine 50mg may be responsible for causing drowsiness. In case affected you need not drive or use machinery. 

Storage: Procarbazine 50mg Capsules should not be removed from their blister packaging until you are ready to use them. Avoid mixing loose capsules with other loose capsules or tablets. Should be stored in the original container to protect from the moisture. Avoid storing above 25°C.

Where can I buy P-carzine (generic procarbazine hydrochloride) in India?

The procarbazine 50mg price in india is absolutely reasonable, and can be bought from any WHO-GDP as well as ISO certified pharmaceutical company. Prices may vary from non-branded to branded drugs.

The procarbazine cost (P carzine 50 mg) for a strip of 10 capsules is around 337 INR. 

NOTE: The piece of information provided about Procarbazine and Hodgkin's Lymphoma in this article is just for informational purposes and is not served as a substitute for the medical treatment, consultation, diagnosis of an experienced or qualified healthcare practitioner. And in order to know more about this medicinal product, click on the procarbazine 50mg.

FDA Approved medicines in order to treat Hodgkin`s Lymphoma:

• Ambochlorine (Chlorambucil)
• Adcetris (Brentuximab Vedotin)
• ABVD (drug combination including Adriamycin, Bleomycin, Vincristine Sulfate, and Dacarbazine)
• ABVE (drug combination including Adriamycin, Bleomycin, Vincristine Sulfate, and Etoposide)
• ABVE-PC (drug combination including Adriamycin, Bleomycin, Vincristine Sulfate, Etoposide, Prednisone, and Cyclophosphamide)
• BEACOPP (drug combination including Bleomycin, Etoposide, Adriamycin, Cyclophosphamide, Oncovin, Procarbazine and  Prednisolone)
• Becenum (Carmustine)
• BiCNU (Carmustine)
• Blenoxane (Bleomycin)
• Bleomycin injection
• Leukeran (Chlorambucil)
• Brentuximab Vedotin
• Carmubris (Carmustine)
• Carmustine
• DTIC-Dome (Decarbazine)
• Dacarbazine
• Cytoxan (Cyclophosphamide)
• Cyclophosphamide
• Claflen (Cyclophosphamide)
• Chlorambucil
• Doxorubicin Hydrochloride
• ICE (drug combination including Ifosfamide, Carboplatin, and Etoposide)
• OEPA (drug combination including Oncovin, Etoposide, Prednisone, and Adriamycin)
• OPPA (drug combination including Oncovin, Procarbazine Hydrochloride, Prednisone, and Adriamycin)
• Prednisone
• Procarbazine Hydrochloride
• STANFORD V (drug combination including Cyclophosphamide, Mechlorethamine or Ifosfamide in addition to Doxorubicin, Vinblastine, Vincristine, Bleomycin, Etoposide, and Prednisone)
• VAMP (drug combination including Vincristine Sulfate, Adriamycin, Methotrexate, and Prednisone)
• Velban (Vinblastine Sulfate)
• Velsar (Vinblastine Sulfate)
• Vinblastine Sulfate
• Vincasar PFS (Vincristine Sulfate)
• Vincristine Sulfate

Affecting Terms:
In this segment, there are few terms are given that might be the probable factor that could increase Hodgkin`s Lymphoma. Which are as follows:

• Age: Hodgkin`s Lymphoma may affect all the age group people but mostly between 20-35 as well as those who persons are above 55 years old.
• Genetics: If someone having any Family Background then there are many chances of this disease.
• Being male: Hodgkin`s Lymphoma most commonly hit to males in comparison to the females.

FAQ's

What were your first symptoms of Hodgkin's lymphoma?

The most common symptom is enlargement or swelling of one or more lymph nodes, causing a lump under the skin, usually doesn't hurt. It's most often on the side of the neck, in the groin or armpit. 

Is Hodgkin's lymphoma a death sentence?

The existing treatments are quite effective for certain types of lymphoma, specifically HL (Hodgkin's lymphoma), in case detected early on. In fact, the medical advances over the last some years have made HL one of the most curable forms of cancer.

What are hodgkin's lymphoma stages? 

As with most other cancers, there are basically 4 different stages of lymphoma: I, II, III, & IV.

How long is it possible to live after Hodgkin's lymphoma treatment?

The 5-year SR refers to the% of patients, on behalf of the stage of their cancer at diagnosis, who live at least 5-years following the hodgkin lymphoma treatment. Numerous of these patients generally live longer than the 5-years.

Is Hodgkin lymphoma curable?

Treatment for the HL (Hodgkin lymphoma) is highly effective and most patients with the disease are eventually cured.

All About Dactinomycin

Dactinomycin is a chemotherapy agent belongs to the category of “antitumor antibiotic” Dactinomycin is available as 0.5mg Injection. dactinomycin 0.5 mg is recommended for the treatment of several types of cancer as per following details:

• Gestational trophoblastic neoplasia
• Wilms' tumor
• Testicular cancer
• Childhood Rhabdomyosarcoma
• Ovarian (germ cell) cancer
• Gestational trophoblastic neoplasm
• Ewing's sarcoma
• Metastatic testicular tumors (non seminomatous)
• Gestational trophoblastic neoplasm
• Locally recurrent or loco regional solid tumors (sarcomas, carcinomas and adenocarcinomas)
• Soft tissue sarcoma
• Osteosarcoma

The innovator brand of Dactinomycin is Cosmegen. Cosmegen was approved by FDA USA in 1982. Dactinomycin is available as .5 mg / vial

There are many generic brands of Dactinomycin available in India as per follows:

1.  Dacilon 0.5mg Injection, Celon Labs
2.  Actinocin 0.5mg Injection, Neon Laboratories Ltd
3.  Tinowel 0.5mg Injection, Getwell Oncology Pvt Ltd
4. Dacmozen 0.5mg Injection, VHB Life Sciences Inc
5. Daltepin – Intas
6.  Dactino - Chandra Bhagat Pharma

Dactinomycin0.5mg Injection works by interfering with the growth of cancer cells, which are eventually destroyed. Dactinomycin is given under the supervision of a healthcare professional and should not be self-administered. Dactinomycin might be given as a single therapy or in combination with some other medication.

There are many countries where Dactinomycin is not available or approved. Patients from those countries can import medicine on named patient bases. They have to take import permission from their Government before importing the product. They have to provide their prescription and id proof before importing the product. It is always better to check the credential of the exporter before importing the product.

There is another way for the patient to get access to generic medicines from India. Patients can travel to India for consultation with a qualified Doctor and based on the prescription, they can buy 3-6 months of therapy. Patients need to know the legal requirement of their domicile countries before taking medicine along with them. It is advisable not to buy medicine which contains narcotic substance.

A generic medicine is a broad term. The patient/buyer should check the Credibility of the manufacturer before buying the product.

What is Dactinomycin? 

Dactinomycin or actinomycin D, is a chemo drug used to treat certain cancers including Wilms tumor, Ewing's sarcoma, trophoblastic neoplasm, rhabdomyosarcoma, testicular cancer, and certain types of ovarian cancer.

What class of drug is Dactinomycin?

Dactinomycin falls under the cytotoxic antibiotic family of medications.

How should Dactinomycin be administered? 

Dactinomycin or Actinomycin D injection should be administered by injection into a vein.

Where can I Buy Generic Dactinomycin .5 mg in India?

Patients from all over the world can buy generic Dactinomycin from Pharmacy shops in India. Patients need to consult Hematologist / Oncologists / Physician before starting treatment.     

Can we buy Dactinomycin online?

Dactinomycin is a prescription medicine. The patent should start treatment with Dactinomycin after consultation with treating Physician

What are the commonly reported side effects due to Dactinomycin? 

The most commonly reported side effects include bone marrow suppression, vomiting, muscle pains, mouth ulcers, hair loss, liver problems, and infections. 

What are the long term side effects of Actinomycin D? 

Certain actinomycin D long term side effects may include:

• bone marrow injury
• delayed healing
• congestive heart failure exacerbation
• toxic liver injury
• unexplained or lingering fatigue
• susceptibility to infection
• high risk of new cancer tumors (including leukemia)
• limb constriction
• renal failure 
• skin deformity/scarring
• increased risk of infertility

What if Dactinomycin is used in pregnancy? 

Use of Dactinomycin in pregnancy may harm the baby.

What is the price of Actinomycin D injection? 

The actinomycin D injection price for patients usually varies depending on several different factors, such as geographic location, severity of disease, and the appropriate dactinomycin dosage.

NOTE: The information provided in this article named All About Dactinomycin, is only for informational purposes and is not served as a substitute for the medical treatment, consultation, diagnosis, of a qualified doctor. 

Buy Pomalidomide Online

Pomalidomide is targeted Therapy which is used in the treatment of Multiple Myeloma patients. Pomalidomide is a derivative of Thalidomide. This product is marketed by Celgene. Pomalidomide is anti angiogenic and also acts as an Immunomodulator. Pomalidomide is being marketed as Pomalyst in the U.S. and Imnovid in the Europe and Russia. This product was approved in 2013 by USA FDA for treatment in patients with relapsed and refractory Multiple Myeloma. Pomalidomide is available as Capsule form. Pomalyst or Imnovid is not available in India as of now (December’ 2019). The only option is to buy Generic version of Pomalidomide in India.

The cost of Pomalyst will be very high as the patient requiring Pomalyst will have to import the product on named patient supply. The Indian Government may not allow the import of Innovator product (Pomalyst / Imnovid) if Generic is available in India.

The 1^st genetic of Pomalidomide was approved in India by Natco Pharma in 2017.  Natco introduces Pomalidomide by the brand name of Pomalid. There are many other generic products available in India as per following details:

1.       Pomyelo,  Intas Pharmaceuticals Ltd

2.       Pomired, Dr Reddy's Laboratories Ltd

3.       Ibipolid,  Indiabulls pharmaceutical ltd

4.       Pomavia, Lupin Ltd

5.       Pomalex, Sun Pharmaceutical Industries Ltd

6.       Pomide, Hetero Pharma

There are many countries where Abiraterone is not available or approved. Patients from those countries can import medicine on named patient bases. They have to take import permission from their Government before importing the product. They have to provide their prescription and id proof before importing the product. It is always better to check the credential of the exporter before importing the product.

 There is another way for the patient to get access to the generic medicines from India. Patients can travel to India for consultation with a qualified Doctor and based on the prescription, they can buy 3-6 month of therapy. Patients need to know the legal requirement of their domicile countries before taking medicine along with them. It is advisable not to buy medicine which contains narcotic substance.

Generic medicine is a broad term. Patient / buyer should check Credibility of manufacturer before buying the product.

Where can I Buy Generic Pomalidomide 4 mg in India?

Patients from all over the world can buy generic pomalidomide 4 mg from Pharmacy shops in India. Patients need to consult Hematologist / Oncologists / Physician before starting treatment.    

Can we buy Pomalidomide online?

Pomalidomide is a prescription medicine. The patent should start treatment with Pomalidomide after consultation with treating Physician

buy otezla online in india

Apremilast is an immunomodulating agent used in the treatment of certain types of psoriasis and psoriatic arthritis. This product was approved by FDA USA in 2014. Apremilast was developed by Celgene Corporation. The product was launched by the brand name of Otezla. otezla 30 mg is available as oral form.

Aprezo is the generic the brand launched by Glenmark Pharmaceuticals Ltd,Aprezo is available as

There is only many Generic brands available in India. The details are as follows:

Aplex 30mg Tablet, Ajanta Pharma Ltd

Pdlast Tablet, Sun Pharmaceutical Industries Ltd

Aprenext 30mg Tablet, Indiabulls pharmaceutical ltd

Arthlast Tablet, Wallace Pharmaceuticals Pvt Ltd

Apxenta Tablet, Ajanta Pharma Ltd

Riasis 30mg Tablet, Zydus Cadila

Apraize 30mg Tablet, Ipca Laboratories Ltd

Apremist 30mg Tablet, Corona Remedies Pvt Ltd

Pravy 30mg Tablet, Dr Reddy's Laboratories Ltd

Alizap 30mg Tablet, Biocon

Mprila Tablet, Mylan Pharmaceuticals Pvt Ltd

Aplavia 30mg Tablet, Zydus Cadila

All these generic products are available in the pack size of 10 tablets. The price varies from 198 to 275 for pack containing 10 tablets. There is significant price advantage in buying generic version of Apremilast. 

There are many countries where Apremilast is not available or approved. Patients from those countries can import medicine on named patient bases. They have to take import permission from their Government before importing the product. They have to provide their prescription and id proof before importing the product. It is always better to check the credential of the exporter before importing the product.

There is another way for the patient to get access to the generic medicines from India. Patients can travel to India for consultation with a qualified Doctor and based on the prescription, they can buy 3-6 month of therapy. Patients need to know the legal requirement of their domicile countries before taking medicine along with them. It is advisable not to buy and medicine which contains narcotic substance.

Generic medicine is a broad term. Patient / buyer should check Credibility of manufacturer before buying the product.

Where can I Buy Aprezo in India?

Patients from all over the world can buy generic Aprezo from Pharmacy shops in India. Patients need to consult Physician / Dermatologist before starting treatment.

     

Can we buy Aprezo online?

aprezo apremilast tablets is a prescription medicine. The patent should start treatment with Aprezo after consultation with treating Physician


READ MORE FOR MORE INFORMATION:-

Best Treatment for Psoriatic Arthritis

Rheumatoid Arthritis Symptoms and Treatment

Buy Imbruvica (Ibrutinib 140 mg) online in India at lowest price

Ibrutinib is a small molecule drug that binds permanently to a protein Bruton's tyrosine kinase (BTK). Ibrutinib is indicated for B cell Cancers e.g. Mentle cell Lymphoma (who has received at least one prior treatment), Chronic Lymphocytic Leukemia (CLL) and small Lymphocytic Leukemia (SLL) etc.

Ibrutinib was jointly developed and commercialized by Janssen Biotech and AbbVie Company Pharmacyclics.

The 1^st approval of Ibrutinib was granted by USA FDA in 2013. This is available as brand name Imbruvica in 90 and 120 packs. The print price of Imbruvica 140 mg capsules (90 tablet packs) is 328000 INR. There was no generic available till 2016. Following four brands were introduced by manufacturing companies based in Bangladesh in 2016.

Brand Name	Dosage Form	Strength	Company
Ibrucent	Capsule	140 mg	Incepta Pharmaceuticals Limited
Ibrunib	Capsule	140 mg	Julphar Bangladesh Ltd.
Ibrutinix	Capsule	140 mg	Everest Pharmaceuticals Ltd.
Ibrutix	Capsule	140 mg	Beacon Pharmaceuticals Ltd.

Indian patients did not have any choice till December’2019 but to buy innovator brand which was very expensive. Natco (Pharmaceutical company based in India) Introduced generic version of Ibrutinib 140 mg by the brand name of Ibrunat in December’2019. The details are as follows:

Brand Name: Ibrunat

Generic Composition: Ibrutinib 140 mg

Strength: 140 mg

Packing: Pack of 30 capsules

Price / pack: 9500 INR

Generic Ibrutinib will help many more patients in getting access to the treatment. Most of the patients were not able to afford innovators product as the price was very high. The difference in price is significant. Each capsule of Imbruvica costs 3644 INR whereas the price of one capsule of Ibrunat is 105 INR. Innovator brand is 34 times more expensive.

Uses and the side effects of the Gefitinib 250 mg tablet

Uses- Gefitinib is a Chemotherapy medication and its Commercially received approval by FDA in 2003 for the Treatment of patients with Advanced or Metastatic Non-small cell lung cancer whose tumors have specific Mutation in the gene for the Epidermal growth factor Receptor. Gefitinib (Innovator Band- Iressa) blocks a certain type of Protein (An enzyme called Tyrosine Kinase) and interferes with the growth of cancer cells and slows their growth and spread in the body.

Side Effects-  Diarrhea, rash, acne, nausea, vomiting, loss of appetite, nail problems, hair loss, red/sore mouth or throat, Symptoms of Dehydration (Dizziness, dry mouth, fast heartbeat) or unusual weakness may occur if you are on the Treatment of Gefitinib (Geftinat 250 mg by Natco Pharma). If any these side effects Persist please notify your doctor Immediately. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Storage- Store at room temperature between 20-25 degrees C away from light and moisture.
Iressa/Geftinat (Gefitinib) Availability in India:

Brand Choice- Iressa 250 mg (Manufactured by Astra Zeneca Canada Inc.) and this is available in India also, cost goes around $220 USD for 30 Tablets.

Generic Choice- In India, many generics are available like gefitinib 250 mg by Natco and Geftib by Glenmark etc. Geftinat price in India goes around $80 to $100 USD for 30 Tablets & gefitinib tablet price in china $60 to $80 USD. Patients can purchase online in India.

Read-  Lung cancer and their Treatments​